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Structure of 115591-65-6
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Methyl 4-chloro-2-(trifluoromethyl)benzoate features a trifluoromethyl group flanked by a chlorine substituent on a methyl benzoate scaffold, delivering enhanced electron-withdrawing character and improved metabolic stability. This combination enables efficient incorporation into pharmaceutical intermediates and functional materials requiring robust aromatic frameworks under standard conditions.
Methyl 4-chloro-2-(trifluoromethyl)benzoate serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct functionalization at the aromatic ring due to orthogonal directing effects of the chloro and trifluoromethyl groups. Its ester functionality facilitates downstream transformations including hydrolysis, nucleophilic substitution, and cross-coupling reactions. The molecule exhibits excellent bench stability, mild handling requirements, and compatibility with standard purification techniques, making it well-suited for iterative synthetic sequences in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: