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CS-W001157 4
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5-Bromoacetyl-2-hydroxybenzaldehyde

  • CAS No. 115787-50-3

  • Cat. No. CS-M2582
  • Purity≥95%
  • MDL No.MFCD09833486

*For research and further manufacturing use only, not for direct human use.

5-Bromoacetyl-2-hydroxybenzaldehyde|CS-M2582

Structure of 115787-50-3

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General Information

  • CAS No. 115787-50-3
  • Cat. No. CS-M2582
  • Purity ≥95%
  • MDL No. MFCD09833486
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇BrO₃
  • Molecular Weight 243.05
  • Synonym(s) 5-(2-Bromoacetyl)-2-hydroxybenzaldehyde
  • SMILES O=CC1=CC(C(CBr)=O)=CC=C1O

Description

5-Bromoacetyl-2-hydroxybenzaldehyde features a brominated acetyl group flanked by a phenolic hydroxyl and aldehyde moiety, enabling direct integration into heterocyclic scaffolds. This trifunctional platform supports efficient coupling reactions under mild conditions, offering enhanced stability and solubility in polar solvents for synthetic applications.

Application

5-Bromoacetyl-2-hydroxybenzaldehyde serves as a versatile synthetic building block for the construction of heterocyclic scaffolds and functionalized aromatic systems. The molecule combines a bromoacetyl group for further coupling reactions, a phenolic hydroxyl for derivatization or protection, and an aldehyde functionality enabling condensation and imine formation. Its bench-stable nature and compatibility with standard purification methods facilitate use in multi-step synthesis workflows.

Synthesis

  • Route1
    • null|null
      90-02-8
    • null|null
      598-21-0
    • ~82%
    • In-stock
      5-Bromoacetyl-2-hydroxybenzaldehyde|CS-M2582
      115787-50-3

    References

    • Liu, Anqiu; Huang, Ling; Wang, Zhiren; Luo, Zonghua; Mao, Fei; Shan, Wenjun; Xie, Jiaxing; Lai, Kefang; Li, Xingshu Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 5 p. 1548 - 1552
  • Route2
    • null|null
      22118-09-8
    • null|null
      90-02-8
    • ~67%
    • In-stock
      5-Bromoacetyl-2-hydroxybenzaldehyde|CS-M2582
      115787-50-3

    References

    • Rong, Yajing; Ruoho, Arnold E. Synthetic Communications, 1999 , vol. 29, # 12 p. 2155 - 2162
  • Route3
    • null|null
      22118-09-8
    • null|null
      90-02-8
    • ~%
    • null|null
      115787-51-4
    • In-stock
      5-Bromoacetyl-2-hydroxybenzaldehyde|CS-M2582
      115787-50-3

    References

    • Synthesis, , # 12 p. 966 - 972

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   54.37
  • LogP   1.7823
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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