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Structure of 1158331-26-0
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Methyl 7-fluoro-1H-indole-2-carboxylate features a fluorinated indole core with enhanced electron-withdrawing character, enabling efficient coupling in cross-coupling and cyclization reactions. This bench-stable derivative integrates readily into synthetic routes for bioactive heterocycles, offering improved solubility and reactivity compared to non-fluorinated analogs.
Methyl 7-fluoro-1H-indole-2-carboxylate serves as a versatile building block for the synthesis of fluorinated indole derivatives. The methyl ester group enables straightforward functionalization via hydrolysis, reduction, or coupling reactions, while the 7-fluoro substitution enhances electrophilic reactivity at C6 and facilitates subsequent C–H functionalization. Bench-stable and compatible with standard synthetic workflows, it functions as a key intermediate in the construction of bioactive heterocycles and pharmaceutical scaffolds.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: