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CS-W001157 4
Total: USD 88.00

5-Propargylamino-dCTP

  • CAS No. 115899-39-3

  • Cat. No. CS-0149518
  • Purity≥98%
  • MDL No.MFCD28010326
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Propargylamino-dCTP|CS-0149518

Structure of 115899-39-3

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Description

5-Propargylamino-dCTP integrates a propargylamine handle into the cytidine scaffold, enabling site-specific bioconjugation via copper-catalyzed azide-alkyne cycloaddition. This modified nucleotide incorporates efficiently into DNA during synthesis, offering a robust strategy for labeling oligonucleotides with minimal perturbation to duplex stability.

Application

5-Propargylamino-dCTP serves as a versatile nucleoside triphosphate analog for site-specific incorporation into DNA during enzymatic synthesis. Its propargylamino group enables bioorthogonal conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC), facilitating downstream labeling, affinity capture, or probe immobilization. The compound exhibits good stability under standard polymerase reaction conditions and supports efficient enzymatic extension, making it suitable for applications in DNA tagging, sequencing, and synthetic biology workflows.

General Information

  • CAS No. 115899-39-3
  • Cat. No. CS-0149518
  • Purity ≥98%
  • MDL No. MFCD28010326
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₉N₄O₁₃P₃
  • Molecular Weight 520.22
  • Synonym(s) None
  • SMILES O=[P](O[P](O[P](O)(O)=O)(O)=O)(O)OC[C@@H](O1)[C@@H](O)C[C@@H]1N(C2=O)C=C(C(N)=N2)C#CCN

Computational Chemistry Data

  • TPSA   276.21
  • LogP   -1.8726
  • H_Acceptors   13
  • H_Donors   7
  • Rotatable_Bonds   8

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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