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*For research and further manufacturing use only, not for direct human use.
Structure of 1159408-54-4
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TLR4-IN-C34-C2-COOH is a potent, selective inhibitor of Toll-like receptor 4 signaling, designed for precise modulation of innate immune responses. This compound features a carboxylic acid terminus enabling conjugation and bioconjugation applications. Its structure incorporates a hydrophobic core that enhances membrane permeability and target engagement. Bench-stable under standard conditions, it facilitates robust in vitro and cellular assays.
TLR4-IN-C34-C2-COOH serves as a well-characterized Toll-like receptor 4 (TLR4) antagonist scaffold, enabling selective inhibition in innate immune signaling pathways. Its carboxylic acid functionality facilitates conjugation and derivatization for probe development, while the C34-C2 backbone offers enhanced metabolic stability and solubility. Functions effectively in cellular assays to modulate inflammatory responses, making it a practical tool for immunopharmacology research and target validation studies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: