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Structure of 1161362-01-1
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This trifluoromethyl-substituted phenylacetic acid delivers a potent electron-withdrawing group flanking a reactive carboxylic acid, enabling efficient coupling in cross-coupling and functionalization workflows. Its moisture-tolerant stability simplifies handling in synthetic sequences requiring precise aryl modifications.
3-Bromo-5-(trifluoromethyl)phenylacetic acid serves as a versatile building block for the synthesis of bioactive molecules, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo substituent and carboxylic acid functionality. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the phenylacetic acid scaffold provides a platform for further derivatization in medicinal chemistry. The compound exhibits good bench stability and is readily purified by recrystallization or chromatography, facilitating integration into standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: