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CS-W001157 4
Total: USD 88.00

4-Fluoro-N-methoxy-N-methylbenzamide

  • CAS No. 116332-54-8

  • Cat. No. CS-0042878
  • Purity≥95%
  • MDL No.MFCD02179265
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Fluoro-N-methoxy-N-methylbenzamide|CS-0042878

Structure of 116332-54-8

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Description

Ethyl p-toluenesulfonate was used to develop an extraction method for methyl and ethyl esters of various sulfonic acids in active pharmaceutical ingredients using solid-phase micro extraction coupled to GC/MS in the selected ion monitoring mode. It was used in a study to develop a fast and accurate method for determination of residues of some common alkylating agents employed in drug synthesis by in situ derivatization-headspace-gas chromatography-mass spectrometry.

Application

4-Fluoro-N-methoxy-N-methylbenzamide serves as a versatile building block in medicinal chemistry, enabling efficient amide bond formation and serving as a key intermediate in the synthesis of heterocyclic scaffolds. Its fluorinated aryl group enhances metabolic stability, while the N-methoxy-N-methyl substitution facilitates controlled reactivity in coupling reactions. The compound exhibits excellent bench stability and is compatible with standard purification protocols, making it well-suited for iterative synthetic workflows in API development.

General Information

  • CAS No. 116332-54-8
  • Cat. No. CS-0042878
  • Purity ≥95%
  • MDL No. MFCD02179265
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀FNO₂
  • Molecular Weight 183.18
  • Synonym(s) Benzamide, 4-fluoro-N-methoxy-N-methyl-
  • SMILES O=C(N(OC)C)C1=CC=C(F)C=C1

Computational Chemistry Data

  • TPSA   29.54
  • LogP   1.4591
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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