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Structure of 116332-54-8
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Ethyl p-toluenesulfonate was used to develop an extraction method for methyl and ethyl esters of various sulfonic acids in active pharmaceutical ingredients using solid-phase micro extraction coupled to GC/MS in the selected ion monitoring mode. It was used in a study to develop a fast and accurate method for determination of residues of some common alkylating agents employed in drug synthesis by in situ derivatization-headspace-gas chromatography-mass spectrometry.
4-Fluoro-N-methoxy-N-methylbenzamide serves as a versatile building block in medicinal chemistry, enabling efficient amide bond formation and serving as a key intermediate in the synthesis of heterocyclic scaffolds. Its fluorinated aryl group enhances metabolic stability, while the N-methoxy-N-methyl substitution facilitates controlled reactivity in coupling reactions. The compound exhibits excellent bench stability and is compatible with standard purification protocols, making it well-suited for iterative synthetic workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: