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Structure of 1167056-95-2
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4-Fluoro-7-nitro-1H-indole features a strategically positioned fluorine atom and nitro group on the indole core, enabling enhanced electron deficiency for directed functionalization. This combination delivers high reactivity in cross-coupling and transition-metal-catalyzed transformations, particularly under mild conditions. The molecule exhibits excellent stability during handling and storage, making it well-suited for synthetic workflows requiring precise regiocontrol and predictable reaction outcomes.
4-Fluoro-7-nitro-1H-indole serves as a versatile building block for the synthesis of functionalized indole scaffolds in medicinal chemistry and materials science. The ortho-fluoro and nitro substituents enable directed metalation and subsequent cross-coupling reactions, while maintaining bench stability and compatibility with standard purification protocols. This compound facilitates access to complex heterocyclic systems through sequential transformations, including nitro reduction and electrophilic substitution.
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GHS Pictogram :
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GHS No : GHS08
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H341
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Precautionary Statements : P280-P405-P501
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Lot numbers can be found on the outside label of a product: