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Structure of 116986-08-4
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Methyl 2-(bromomethyl)nicotinate is a brominated pyridine derivative featuring a reactive bromomethyl group at the 2-position. This electrophilic handle enables facile functionalization in cross-coupling and nucleophilic substitution reactions. The ester moiety enhances solubility and compatibility with synthetic workflows, while the molecule exhibits bench-stable handling under standard conditions.
Methyl 2-(bromomethyl)nicotinate serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. The bromomethyl group enables efficient nucleophilic substitution reactions, facilitating C–C and C–heteroatom bond formation under mild conditions. Its stability under standard bench handling and compatibility with diverse functional groups make it well-suited for iterative synthetic strategies in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: