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Structure of 1178420-52-4
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2-(3,5-Dichlorophenyl)thiazole-4-carboxylic acid features a rigid thiazole core flanked by electron-withdrawing dichlorophenyl and carboxylic acid groups, enabling robust integration into bioactive scaffolds. This moisture-tolerant, bench-stable compound facilitates direct coupling in medicinal chemistry campaigns requiring halogenated heterocycles.
2-(3,5-Dichlorophenyl)thiazole-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of thiazole-based heterocycles with enhanced bioavailability. Its robust functional group tolerance facilitates downstream derivatization via amide coupling, esterification, and Suzuki-Miyaura cross-coupling reactions. The molecule exhibits excellent bench stability and is readily purified by recrystallization, making it ideal for high-throughput screening and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: