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Structure of 117943-07-4
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1,2,4,5-Tetrazine-3,6-dicarboxylic acid features a highly electron-deficient tetrazine core paired with two carboxylic acid groups, enabling efficient bioorthogonal conjugation. This scaffold integrates readily into probe designs for live-cell labeling and molecular imaging, offering fast reaction kinetics with strained cyclooctynes under physiological conditions.
1,2,4,5-Tetrazine-3,6-dicarboxylic acid serves as a versatile building block for bioorthogonal conjugation and heterocyclic synthesis. Its electron-deficient tetrazine core enables efficient inverse electron-demand Diels–Alder (IEDDA) reactions with strained dienophiles, facilitating rapid labeling under physiological conditions. The dicarboxylic acid functionality enhances solubility and provides handles for derivatization or solid-phase immobilization, supporting applications in probe development, peptide conjugation, and targeted drug delivery systems.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: