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CS-W001157 4
Total: USD 88.00

Sodium pivalate

  • CAS No. 1184-88-9

  • Cat. No. CS-W006398
  • Purity≥97%
  • MDL No.MFCD00064202

*For research and further manufacturing use only, not for direct human use.

Sodium pivalate|CS-W006398

Structure of 1184-88-9

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General Information

  • CAS No. 1184-88-9
  • Cat. No. CS-W006398
  • Purity ≥97%
  • MDL No. MFCD00064202
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉NaO₂
  • Molecular Weight 124.11
  • Synonym(s) Trimethylacetic acid sodium salt
  • SMILES [Na].O=C(O)C(C)(C)C

Description

3,4-Dimethylbenzenesulfonyl chloride is used as an intermediate.

Application

Sodium pivalate serves as a stable, bench-ready source of the pivaloyl group, enabling efficient acylation reactions under mild conditions. Its high solubility in polar solvents and resistance to hydrolysis enhance utility in peptide synthesis and esterification protocols. Functions reliably as a protecting group precursor and facilitates clean derivatization in complex molecule assembly.

Synthesis

  • Route1

    References

    • DeRosa, Frank; Keefer, Larry K.; Hrabie, Joseph A. Journal of Organic Chemistry, 2008 , vol. 73, # 3 p. 1139 - 1142
  • Route2
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      1310-73-2
    • In-stock
      Pivalic acid|CS-D1464
      75-98-9
    • ~%
    • In-stock
      Sodium pivalate|CS-W006398
      1184-88-9

    References

    • Bazhina, Evgenia S.; Nikiforova, Marina E.; Aleksandrov, Grigory G.; Efimov, Nikolay N.; Ugolkova, Helena A.; Nikitin, Oleg M.; Magdesieva, Tatiana V.; Bogomyakov, Artem S.; Minin, Vadim V.; Sidorov, Aleksei A.; Novotortsev, Vladimir M.; Eremenko, Igor L. Inorganica Chimica Acta, 2012 , vol. 392, p. 192 - 198
  • Route3
    • null|null
      85055-92-1
    • ~%
    • null|null
      4425-82-5
    • In-stock
      Sodium pivalate|CS-W006398
      1184-88-9

    References

    • O'Ferrall, Rory A. More; Larkin, Finbar; Walsh, Peter Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1982 , p. 1573 - 1580

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 2789
Class : 8 (3)
Packing Group : Ⅱ
Hazard Statements : H226-H314
Precautionary Statements : P210-P233-P240-P280-P303+P361+P353-P305+P351+P338

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   0.4686
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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