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CS-W001157 4
Total: USD 88.00

4-(Prop-2-yn-1-yloxy)piperidine hydrochloride

  • CAS No. 1185100-09-7

  • Cat. No. CS-0231337
  • Molecule weight175.66
  • Purity≥98%
  • MDL No.MFCD09475417

*For research and further manufacturing use only, not for direct human use.

4-(Prop-2-yn-1-yloxy)piperidine hydrochloride|CS-0231337

Structure of 1185100-09-7

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General Information

  • CAS No. 1185100-09-7
  • Cat. No. CS-0231337
  • Purity ≥98%
  • MDL No. MFCD09475417
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₄ClNO
  • Molecular Weight 175.66
  • Synonym(s) None
  • SMILES Cl.C#CCOC1CCNCC1

Description

This piperidine derivative features a propargyloxy-functionalized heterocycle, enabling efficient conjugation via copper-catalyzed azide-alkyne cycloaddition. The hydrochloride salt enhances solubility and stability under standard handling conditions, facilitating integration into bioconjugation workflows and medicinal chemistry campaigns requiring robust, modular linkers.

Application

4-(Prop-2-yn-1-yloxy)piperidine hydrochloride serves as a versatile building block for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, enabling efficient access to triazole-linked scaffolds. The propargylic ether functionality exhibits excellent bench stability and compatibility with diverse functional groups, facilitating straightforward purification and integration into medicinal chemistry campaigns. Its hydrochloride salt form enhances solubility and handling in aqueous and polar organic media.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P501

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   0.81
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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