Lot numbers can be found on the outside label of a product:
tert-Butyl 3-methoxy-4-oxopiperidine-1-carboxylate
-
CAS No. 1188265-31-7
- Cat. No. CS-0054431
- Purity≥95%
- MDL No.None
*For research and further manufacturing use only, not for direct human use.
Structure of 1188265-31-7
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 1188265-31-7
- Cat. No. CS-0054431
- Purity ≥95%
- MDL No. None
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₁H₁₉NO₄
- Molecular Weight 229.27
- Synonym(s) 3-Methoxy-4-oxo-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
- SMILES COC1CN(CCC1=O)C(=O)OC(C)(C)C
Description
tert-Butyl 3-methoxy-4-oxopiperidine-1-carboxylate features a masked piperidinone scaffold with orthogonal protection, enabling selective functionalization at the nitrogen and carbonyl sites. The methoxy group enhances solubility and modulates reactivity, while the tert-butyl ester provides stability under basic conditions and facilitates clean deprotection. This intermediate supports efficient access to complex nitrogen-containing architectures in medicinal chemistry and natural product synthesis.
Application
tert-Butyl 3-methoxy-4-oxopiperidine-1-carboxylate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to piperidine-based scaffolds. The protected amine and ketone functionalities offer orthogonal reactivity for selective transformations, while the tert-butoxycarbonyl (Boc) group provides bench stability and ease of removal under mild acidic conditions. Its methoxy substituent enhances solubility and modulates electronic effects, facilitating downstream functionalization in medicinal chemistry and process development workflows.
Synthesis
-
Route1
-
942945-28-0 -
In-stock
24424-99-5 - ~%
-
In-stock
1188265-31-7
References
-
CONVERGENCE PHARMACEUTICALS LIMITED; WITTY, David R.; NORTON, David; TIERNEY, Jason Paul; LORTHIOIR, Ghislaine; SIME, Mairi; PHILPOTT, Karen Louise Patent: WO2012/80735 A1, 2012 ; Location in patent: Page/Page column 9; 32; 33 ; WO 2012/080735 A1
-
-
Route2
-
79099-07-3
- ~%
-
In-stock
1188265-31-7
References
-
CONVERGENCE PHARMACEUTICALS LIMITED; WITTY, David R.; NORTON, David; TIERNEY, Jason Paul; LORTHIOIR, Ghislaine; SIME, Mairi; PHILPOTT, Karen Louise Patent: WO2012/80735 A1, 2012 ; WO 2012/080735 A1
-
-
Route3
-
In-stock
841286-80-4 - ~%
-
In-stock
1188265-31-7
References
-
CONVERGENCE PHARMACEUTICALS LIMITED; WITTY, David R.; NORTON, David; TIERNEY, Jason Paul; LORTHIOIR, Ghislaine; SIME, Mairi; PHILPOTT, Karen Louise Patent: WO2012/80735 A1, 2012 ; WO 2012/080735 A1
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 55.84
- LogP 1.2113
- H_Acceptors 4
- H_Donors 0
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 1188265-31-7 sigma1188265-31-7 manufacturer1188265-31-7 price1188265-31-7 structure1188265-31-7 SDSbuy 1188265-31-71188265-31-7 supplier1188265-31-7 uses1188265-31-7 molecular weightprice of 1188265-31-71188265-31-7 chemical name formula of 1188265-31-7