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Structure of 1189458-67-0
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4,4'-Difluoro-2,2'-bipyridine features a rigid bidentate scaffold with fluorine substituents that enhance electron deficiency and improve solubility in polar solvents. This configuration enables efficient coordination to transition metals in catalytic systems, particularly in photoredox and cross-coupling applications. The molecule exhibits bench-stable handling under standard conditions and integrates readily into complex ligand architectures.
4,4'-Difluoro-2,2'-bipyridine serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl architectures under palladium- or nickel-mediated conditions. The difluorinated substitution pattern enhances both electronic modulation and metabolic stability in target scaffolds, while the bipyridyl core provides strong chelation for metal complexes. Bench-stable and readily purified by column chromatography, it functions effectively in standard synthetic workflows for pharmaceutical and materials chemistry applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: