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Structure of 1190319-16-4
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5-Bromo-3-iodo-1H-pyrrolo[3,2-b]pyridine features a dual halogenated pyrrolopyridine core enabling efficient cross-coupling transformations. The electron-deficient heterocycle integrates readily into complex architectures, while the ortho-halogen substitution pattern supports sequential functionalization. This bench-stable scaffold offers predictable reactivity in palladium-catalyzed processes.
5-Bromo-3-iodo-1H-pyrrolo[3,2-b]pyridine serves as a versatile dual-heteroatom-functionalized building block for transition-metal-catalyzed cross-coupling reactions. The bromo and iodo substituents enable sequential or orthogonal coupling with boronic acids, amines, and thiols under palladium or nickel catalysis, facilitating rapid access to complex polycyclic scaffolds. Its bench-stable crystalline form and predictable regioselective reactivity make it ideal for medicinal chemistry campaigns and API intermediate synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: