5-Fluoro-1H-pyrrolo[2,3-c]pyridine

Name: 5-Fluoro-1H-pyrrolo[2,3-c]pyridine
Brand: ChemScene
Availability: InStock
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CAS No. 1190319-70-0
Cat. No. CS-0040220
Purity≥98%
MDL No.MFCD12962571

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FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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5-Fluoro-1H-pyrrolo[2,3-c]pyridine|CS-0040220

Structure of 1190319-70-0

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Description

5-Fluoro-1H-pyrrolo[2,3-c]pyridine is a heteroaromatic scaffold featuring a fluorine atom at the 5-position, enhancing electron deficiency and metabolic stability. This moiety integrates readily into kinase inhibitors and CNS-targeted pharmaceuticals, offering improved binding affinity and solubility profiles under standard conditions.

Application

5-Fluoro-1H-pyrrolo[2,3-c]pyridine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of kinase inhibitors and other bioactive molecules. Its fluorinated pyrrolopyridine core offers enhanced metabolic stability and favorable binding interactions. The compound exhibits good bench stability and compatibility with standard coupling reactions, facilitating efficient incorporation into complex scaffolds.

General Information

CAS No. 1190319-70-0
Cat. No. CS-0040220
Purity ≥98%
MDL No. MFCD12962571
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅FN₂
Molecular Weight None
Synonym(s) 5-Fluoro-6-azaindole
SMILES FC1=CC2=C(NC=C2)C=N1

Computational Chemistry Data

TPSA 28.68
LogP 1.702
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
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Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrrole compounds

Key Words

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5-Fluoro-1H-pyrrolo[2,3-c]pyridine

CAS No. 1190319-70-0

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