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Structure of 1192045-84-3
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This boronate ester features a fluorinated methylphenyl group integrated with a stable tetramethyl-1,3,2-dioxaborolane core. The electron-deficient aryl moiety enables efficient coupling in Suzuki-Miyaura reactions, while the steric shielding provided by the tetramethyl groups enhances shelf stability and resistance to protodeboronation under standard conditions.
2-(2-Fluoro-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. Its arylboronate functionality enables efficient coupling with aryl and vinyl halides under mild conditions, offering high functional group tolerance and predictable regiochemistry. The tetramethyl-substituted dioxaborolane ring enhances stability and simplifies purification, making it ideal for iterative synthesis of complex biaryl scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: