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Structure of 1193334-86-9
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4-Bromo-1-cyclopropylpyridin-2(1H)-one features a brominated pyridinone core paired with a cyclopropyl substituent, delivering enhanced metabolic stability and tunable electronic properties. This scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds, offering improved solubility and compatibility with transition-metal-catalyzed coupling reactions under standard conditions.
4-Bromo-1-cyclopropylpyridin-2(1H)-one serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo substituent. The cyclopropyl group enhances metabolic stability and modulates electronic properties, while the pyridin-2-one core provides a hydrogen-bonding scaffold for target engagement. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient synthesis of bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: