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Structure of 1195-98-8
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2-Methyl-2-phenylpropanenitrile features a sterically hindered nitrile group flanked by a phenyl ring and two methyl substituents, delivering enhanced stability and resistance to hydrolysis. This configuration enables efficient incorporation into synthetic routes requiring robust nitrile functionality under standard conditions.
2-Methyl-2-phenylpropanenitrile serves as a robust building block for tertiary nitriles, enabling efficient access to quaternary carbon centers in synthetic routes. Its benzylic nitrile functionality exhibits high bench stability and tolerates diverse reaction conditions, facilitating nucleophilic additions, reductions, and hydrolysis to carboxamides or acids. The molecule's steric bulk enhances regioselectivity in downstream transformations, making it particularly valuable in the construction of complex heterocyclic scaffolds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: