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CS-W001157 4
Total: USD 88.00

4-Bromo-5-methylpicolinic acid

  • CAS No. 1196154-93-4

  • Cat. No. CS-W007217
  • Purity≥98%
  • MDL No.MFCD13190305

*For research and further manufacturing use only, not for direct human use.

4-Bromo-5-methylpicolinic acid|CS-W007217

Structure of 1196154-93-4

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General Information

  • CAS No. 1196154-93-4
  • Cat. No. CS-W007217
  • Purity ≥98%
  • MDL No. MFCD13190305
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrNO₂
  • Molecular Weight 216.03
  • Synonym(s) 4-BroMo-5-Methyl-pyridine-2-carboxylic acid
  • SMILES O=C(O)C1=NC=C(C)C(Br)=C1

Description

4-Bromo-5-methylpicolinic acid features a bromine substituent at the 4-position and a methyl group at the 5-position of the picolinic acid scaffold. This electron-deficient heteroaromatic framework enables direct functionalization in cross-coupling reactions and serves as a key building block for bioactive molecule synthesis under standard conditions.

Application

4-Bromo-5-methylpicolinic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation of bromo and methyl substituents into heterocyclic scaffolds. Its carboxylic acid functionality facilitates amidation, esterification, and coupling reactions under standard conditions. The molecule exhibits bench stability, tolerates common functional groups, and functions effectively in Pd-catalyzed cross-coupling processes for late-stage diversification in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.85072
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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