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Structure of 1197631-00-7
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5-(2-Chlorophenyl)-1H-pyrazole-3-carboxylic acid features a conjugated pyrazole core with a para-chlorinated phenyl substituent and a carboxylic acid handle. This scaffold delivers enhanced solubility and metabolic stability, enabling direct incorporation into bioactive molecules. The electron-deficient aryl ring supports efficient coupling reactions, while the acidic proton facilitates salt formation for improved formulation compatibility.
5-(2-Chlorophenyl)-1H-pyrazole-3-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and agrochemical research. Its structure combines a pyrazole core with an electron-withdrawing carboxylic acid and a 2-chlorophenyl substituent, enabling direct functionalization and coupling reactions. The compound exhibits good bench stability and facilitates efficient derivatization via amide formation, esterification, or metal-catalyzed cross-coupling, supporting rapid scaffold diversification in lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: