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Structure of 1199-07-1
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3-Methylbenzofuran-2-carbaldehyde features a fused benzofuran core with a methyl substituent and a reactive aldehyde group. This electron-deficient heterocycle integrates readily into synthetic scaffolds, serving as a key building block for bioactive molecules. The aldehyde moiety enables efficient coupling reactions under mild conditions.
3-Methylbenzofuran-2-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocyclic scaffolds. Its aldehyde functionality facilitates standard transformations including reductive amination, Wittig reactions, and nucleophilic additions, while the benzofuran core provides structural rigidity and favorable pharmacokinetic properties. The methyl substituent enhances metabolic stability and offers a handle for further functionalization. This compound exhibits good bench stability and is readily purified by flash chromatography, making it well-suited for high-throughput synthesis and lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS03,GHS05
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Signal Word : Danger
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UN#: 1479
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Class : 5.1
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Packing Group : Ⅲ
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Hazard Statements : H272-H314
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Precautionary Statements : P210-P220-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: