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Structure of 1201-24-7
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5-Methyl-1H-indazole-3-carboxylic acid features a fused bicyclic core with a methyl group at the 5-position and a carboxylic acid at the 3-position, offering enhanced solubility and metabolic stability. This scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry for kinase inhibitors and targeted therapeutics.
5-Methyl-1H-indazole-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard amide coupling and electrophilic substitution reactions. Its well-defined functional group pattern—comprising a carboxylic acid at C3 and a methyl group at C5—supports orthogonal reactivity and facilitates purification via crystallization or chromatography. The scaffold exhibits bench stability and compatibility with common protecting group strategies, making it suitable for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: