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Structure of 1201149-04-3
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5-Fluoro-1H-indole-6-carbonitrile integrates a fluorinated indole scaffold with a nitrile handle, enabling direct incorporation into pharmaceutical intermediates. The electron-deficient aromatic system enhances reactivity in transition-metal-catalyzed couplings, while the para-positioned nitrile group supports downstream functionalization. This bench-stable compound serves as a key building block for bioactive heterocycles.
5-Fluoro-1H-indole-6-carbonitrile serves as a versatile building block in medicinal chemistry, enabling direct incorporation of fluorinated indole scaffolds into bioactive molecules. The nitrile group facilitates downstream transformations such as amide formation or reduction to primary amine derivatives, while the 5-fluoro substitution enhances metabolic stability and modulates electronic properties. Bench-stable and compatible with standard coupling reactions, it functions effectively in parallel synthesis campaigns and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: