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CS-W001157 4
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2-(5-Methylpyridin-2-yl)acetic acid hydrochloride

  • CAS No. 1201194-56-0

  • Cat. No. CS-0042617
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(5-Methylpyridin-2-yl)acetic acid hydrochloride|CS-0042617

Structure of 1201194-56-0

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General Information

  • CAS No. 1201194-56-0
  • Cat. No. CS-0042617
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀ClNO₂
  • Molecular Weight 187.62
  • Synonym(s) None
  • SMILES O=C(O)CC1=NC=C(C)C=C1.[H]Cl

Description

This hydrochloride salt features a methyl-substituted pyridine ring linked to a carboxylic acid-bearing acetic side chain, offering enhanced solubility and stability under standard handling conditions. The protonated nitrogen improves crystallinity and facilitates purification in synthetic workflows.

Application

2-(5-Methylpyridin-2-yl)acetic acid hydrochloride serves as a versatile building block for medicinal chemistry and heterocyclic synthesis, enabling efficient access to bioactive scaffolds. The molecule exhibits robust bench stability and facilitates direct incorporation into peptide-like structures or conjugation reactions. Its functional group tolerance supports diverse transformations, including amide formation and metal-catalyzed cross-couplings, making it suitable for both lead optimization and process-scale applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.43892
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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