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Structure of 1201924-31-3
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6-Chloro-3-methylpicolinonitrile features a chlorine atom at the 6-position and a methyl group at the 3-position on a picolinonitrile scaffold. This electron-deficient heterocycle serves as a key building block in medicinal chemistry, enabling efficient coupling reactions via its nitrile and halogen functionalities.
6-Chloro-3-methylpicolinonitrile serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles via palladium-catalyzed cross-coupling and nucleophilic substitution reactions. Its ortho-chloro and nitrile functionalities provide high reactivity for C–C and C–N bond formation, while the methyl group enhances metabolic stability. The compound exhibits excellent bench stability and is readily purified by flash chromatography, facilitating integration into multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: