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Structure of 120422-90-4
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4,6-Dichloro-3-methyl-1H-pyrazolo[4,3-c]pyridine features a fused pyrazolo-pyridine core with dual chlorines at positions 4 and 6, enhancing electrophilic reactivity. The methyl group at C3 provides steric stabilization and improves solubility. This scaffold serves as a key building block for kinase inhibitors and bioactive heterocycles in medicinal chemistry.
4,6-Dichloro-3-methyl-1H-pyrazolo[4,3-c]pyridine serves as a versatile building block for the synthesis of bioactive heterocycles, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. The dichloro substitution pattern facilitates selective derivatization at C4 or C6 positions, while the methyl group enhances solubility and metabolic stability. Its bench-stable crystalline form simplifies handling and purification in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: