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Structure of 120512-59-6
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4-Fluoro-3,5-dimethylbenzoic acid features a fluorinated aromatic core with two methyl groups positioned ortho to the carboxylic acid. This substitution pattern imparts enhanced lipophilicity and metabolic stability, making it valuable for medicinal chemistry applications. The electron-withdrawing fluorine atom fine-tunes acidity and influences binding interactions in target-directed synthesis.
4-Fluoro-3,5-dimethylbenzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated aromatic scaffolds with enhanced metabolic stability. Its ortho-fluorine and methyl groups provide favorable electronic and steric properties for downstream functionalization. The carboxylic acid group facilitates direct coupling reactions and derivatization under standard conditions, offering excellent bench stability and ease of purification in synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: