Methyl 6-chloro-5-(hydroxymethyl)picolinate

Name: Methyl 6-chloro-5-(hydroxymethyl)picolinate
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CAS No. 1205671-72-2
Cat. No. CS-0197753
Purity≥95%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Methyl 6-chloro-5-(hydroxymethyl)picolinate|CS-0197753

Structure of 1205671-72-2

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Description

Methyl 6-chloro-5-(hydroxymethyl)picolinate features a strategically positioned chloro group and a hydroxymethyl side chain on the picolinate scaffold, enabling selective functionalization in synthetic routes. This bench-stable derivative integrates readily into complex molecular architectures, offering enhanced solubility and compatibility in transition metal-catalyzed transformations.

Application

Methyl 6-chloro-5-(hydroxymethyl)picolinate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized heterocyclic scaffolds. The hydroxymethyl group facilitates selective derivatization via oxidation, protection, or substitution reactions, while the chloro and ester functionalities support further transformations such as nucleophilic displacement or cross-coupling. Its bench-stable nature and compatibility with standard purification methods make it well-suited for medicinal chemistry and process development workflows.

General Information

CAS No. 1205671-72-2
Cat. No. CS-0197753
Purity ≥95%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₈ClNO₃
Molecular Weight 201.61
Synonym(s) None
SMILES O=C(OC)C1=NC(Cl)=C(C=C1)CO

Computational Chemistry Data

TPSA 59.42
LogP 1.0139
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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Methyl 6-chloro-5-(hydroxymethyl)picolinate

CAS No. 1205671-72-2

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