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Structure of 1206641-26-0
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This boronate ester features a methylsulfonyl group at the 3-position and a tetramethylboronate handle at the 5-position of a pyridine core. The electron-deficient pyridine ring enhances reactivity in cross-coupling, while the sterically protected boronate moiety ensures stability under standard conditions. This compound integrates readily into Suzuki-Miyaura reactions for constructing complex heteroaromatic scaffolds with high functional group tolerance.
3-(Methylsulfonyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The methylsulfonyl group enhances solubility and provides a stable, electron-withdrawing substituent compatible with diverse reaction conditions. The pinacol boronate moiety enables high functional group tolerance, excellent shelf stability, and facile purification, making it ideal for constructing complex pyridine-based scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: