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Structure of 1206800-18-1
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6-Bromo-1H-indazol-5-ol features a brominated indazol scaffold with a phenolic hydroxyl group at the 5-position, enabling direct functionalization in cross-coupling and derivatization workflows. The electron-deficient core supports efficient palladium-catalyzed transformations, while the hydroxyl moiety offers sites for esterification or metal coordination. This bench-stable compound serves as a key intermediate in medicinal chemistry campaigns targeting kinase inhibitors and bioactive heterocycles.
6-Bromo-1H-indazol-5-ol serves as a versatile building block for the synthesis of biologically active heterocycles, enabling palladium-catalyzed cross-coupling reactions at the bromo position. The phenolic hydroxyl group provides a handle for derivatization and enhances solubility, while the indazolone scaffold offers stability under standard reaction conditions. This compound facilitates efficient access to diversified scaffolds in medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: