10H-Phenothiazine, 10-methyl-

Name: 10H-Phenothiazine, 10-methyl-
Brand: ChemScene
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CAS No. 1207-72-3
Cat. No. CS-0031416
Purity≥98%
MDL No.MFCD00041836

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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10H-Phenothiazine, 10-methyl-|CS-0031416

Structure of 1207-72-3

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Description

10-Methylphenothiazine is a bench-stable, electron-rich heterocycle featuring a methyl-substituted phenothiazine core. This compound serves as a key scaffold in organic synthesis, enabling efficient access to functionalized derivatives through selective oxidation or metal-catalyzed coupling. Its robust stability under standard conditions supports reliable use in process development workflows.

Application

10-Methylphenothiazine serves as a versatile heterocyclic building block in medicinal chemistry, offering enhanced electron-donating character due to the methyl substitution at the 10-position. It functions as a core scaffold in the synthesis of bioactive molecules, particularly in antipsychotic and antimicrobial agents. The compound exhibits good bench stability and facilitates palladium-catalyzed cross-coupling reactions, enabling efficient construction of complex molecular architectures with high functional group tolerance.

General Information

CAS No. 1207-72-3
Cat. No. CS-0031416
Purity ≥98%
MDL No. MFCD00041836
Storage RT, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₁NS
Molecular Weight 213.30
Synonym(s) NSC 120; Phenothiazine, 10-methyl-
SMILES CN1C2=C(SC3=CC=CC=C13)C=CC=C2

Computational Chemistry Data

TPSA 3.24
LogP 3.9191
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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10H-Phenothiazine, 10-methyl-

CAS No. 1207-72-3

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