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Structure of 1209458-12-7
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2-Bromo-6-fluoropyrazine is a halogenated pyrazine derivative featuring complementary reactive sites for cross-coupling. The bromo group enables palladium-catalyzed transformations, while the fluorine atom facilitates nucleophilic substitution or further functionalization. This bifunctional architecture supports modular synthesis in medicinal chemistry and materials science.
2-Bromo-6-fluoropyrazine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The bromine and fluorine substituents offer orthogonal functionalization potential, facilitating sequential derivatization. Its stability under standard synthetic conditions and compatibility with diverse reaction partners make it well-suited for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS02,GHS05,GHS07
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Signal Word : Danger
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UN#: 2924
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Class : 3,8
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Packing Group : Ⅲ
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Hazard Statements : H226-H302-H315-H318-H335
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: