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Structure of 1209459-78-8
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Methyl 2-bromopyrimidine-4-carboxylate features a bromine atom at the 2-position and a methyl ester group at the 4-position of the pyrimidine ring, enabling direct functionalization in cross-coupling reactions. This electron-deficient heterocycle integrates readily into medicinal chemistry scaffolds and serves as a key intermediate for nitrogen-containing bioactive compounds under standard conditions.
Methyl 2-bromopyrimidine-4-carboxylate serves as a versatile building block for the synthesis of pyrimidine-based pharmaceutical intermediates and agrochemicals. Its bromine at the 2-position enables facile palladium-catalyzed cross-coupling reactions, while the ester group offers compatibility with nucleophilic substitution and reduction protocols. The molecule exhibits good bench stability and facilitates efficient functionalization in standard synthetic workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: