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Structure of 1209646-17-2
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This pyrazine-based scaffold integrates a tert-butoxycarbonyl-protected piperazine moiety, offering a stable, moisture-tolerant platform for late-stage diversification in medicinal chemistry. The carboxylic acid functionality enables direct conjugation or salt formation, facilitating downstream derivatization in drug discovery workflows.
5-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyrazine-2-carboxylic acid serves as a versatile building block for constructing bioactive heterocycles in medicinal chemistry. The tert-butoxycarbonyl (Boc) group provides stable protection of the piperazine nitrogen, enabling selective deprotection and derivatization under mild acidic conditions. The pyrazine-2-carboxylic acid moiety offers a rigid, polar scaffold suitable for metal coordination and hydrogen bonding, enhancing target affinity. This compound facilitates efficient synthesis of kinase inhibitors and other pharmaceutical candidates through standard amide coupling and reductive amination protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: