6-Bromo-3-chloro-2-fluoropyridine

Name: 6-Bromo-3-chloro-2-fluoropyridine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1211578-30-1
Cat. No. CS-0139548
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Bromo-3-chloro-2-fluoropyridine|CS-0139548

Structure of 1211578-30-1

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Description

6-Bromo-3-chloro-2-fluoropyridine is a halogenated pyridine scaffold featuring strategically positioned bromo, chloro, and fluoro substituents. This electron-deficient heterocycle enables direct coupling in cross-coupling reactions and serves as a key intermediate in medicinal chemistry for constructing complex nitrogen-containing architectures.

Application

6-Bromo-3-chloro-2-fluoropyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The strategic placement of bromo, chloro, and fluoro substituents allows for sequential functionalization under mild conditions, facilitating the synthesis of complex pyridine-based scaffolds. Its bench-stable nature and compatibility with standard reaction protocols make it ideal for iterative synthesis and process development.

General Information

CAS No. 1211578-30-1
Cat. No. CS-0139548
Purity ≥98%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₂BrClFN
Molecular Weight 210.43
Synonym(s) None
SMILES FC1=NC(Br)=CC=C1Cl

Computational Chemistry Data

TPSA 12.89
LogP 2.6366
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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6-Bromo-3-chloro-2-fluoropyridine

CAS No. 1211578-30-1

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