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Structure of 1211578-46-9
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6-Chloro-2-fluoronicotinic acid features a strategically positioned chloro and fluoro substituent on the nicotinic acid scaffold, enhancing electron-withdrawing character and enabling selective functionalization in medicinal chemistry. This bench-stable derivative integrates readily into heterocyclic synthesis pathways, offering improved solubility and reactivity under standard conditions.
6-Chloro-2-fluoronicotinic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-halogenated pyridine core enables direct functionalization via palladium-catalyzed cross-coupling, while the carboxylic acid group facilitates amide formation and esterification under standard conditions. The molecule exhibits excellent bench stability and compatibility with diverse reaction environments, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: