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Structure of 1211580-54-9
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4-Bromo-2-(difluoromethyl)pyridine features a strategically positioned difluoromethyl group that enhances metabolic stability and modulates electronic properties. This electron-deficient pyridine serves as a key building block in medicinal chemistry, enabling direct incorporation into bioactive molecules via cross-coupling reactions. The bromine moiety provides a high-reactivity handle for further functionalization.
4-Bromo-2-(difluoromethyl)pyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined reactivity profile. The difluoromethyl group imparts enhanced metabolic stability and modulates electronic properties, while the bromopyridine moiety facilitates efficient functionalization via Suzuki-Miyaura or Negishi couplings. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364
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Lot numbers can be found on the outside label of a product: