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Structure of 1211586-66-1
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5-Bromo-4-methoxypyridine-2-carboxylic acid features a pyridine core functionalized with bromo, methoxy, and carboxylic acid groups at strategic positions. This electron-deficient scaffold enables direct coupling in cross-coupling reactions and serves as a key building block for bioactive heterocycles in medicinal chemistry and agrochemical development.
5-Bromo-4-methoxypyridine-2-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions at the bromo position. The carboxylic acid group facilitates direct amidation or esterification, while the methoxy substituent provides moderate electronic modulation and orthogonality in multi-step sequences. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: