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CS-W001157 4
Total: USD 88.00

6-Bromopyrazolo[1,5-a]pyridine-3-carboxylic acid

  • CAS No. 1211596-19-8

  • Cat. No. CS-0012704
  • Purity≥97%
  • MDL No.MFCD11109787

*For research and further manufacturing use only, not for direct human use.

6-Bromopyrazolo[1,5-a]pyridine-3-carboxylic acid|CS-0012704

Structure of 1211596-19-8

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General Information

  • CAS No. 1211596-19-8
  • Cat. No. CS-0012704
  • Purity ≥97%
  • MDL No. MFCD11109787
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrN₂O₂
  • Molecular Weight 241.04
  • Synonym(s) 6-BroMo-pyrazolo[1,5-a]pyridine-3-carboxylic acid
  • SMILES O=C(C1=C2C=CC(Br)=CN2N=C1)O

Description

6-Bromopyrazolo[1,5-a]pyridine-3-carboxylic acid features a brominated pyrazolopyridine core paired with a carboxylic acid group, enabling direct conjugation or derivatization in synthetic workflows. The electron-deficient heterocycle facilitates cross-coupling reactions, while the carboxylic acid serves as a handle for amide formation or metal chelation. This compound offers robust stability under standard conditions and integrates efficiently into complex molecular architectures for medicinal chemistry applications.

Application

6-Bromopyrazolo[1,5-a]pyridine-3-carboxylic acid serves as a versatile building block for the synthesis of biologically active heterocycles, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo and carboxylic acid functionalities. The molecule exhibits bench stability and facilitates efficient derivatization via amide formation or esterification, supporting applications in medicinal chemistry and API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   54.6
  • LogP   1.795
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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