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Structure of 1214334-90-3
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Methyl 2-bromo-4-(trifluoromethyl)benzoate features a bromine atom at the ortho position and a trifluoromethyl group at the para position relative to the ester. This electron-deficient aromatic system enables efficient cross-coupling reactions, particularly in palladium-catalyzed transformations. The compound is bench-stable and compatible with standard reaction conditions, facilitating the synthesis of complex fluorinated biaryl architectures.
Methyl 2-bromo-4-(trifluoromethyl)benzoate serves as a versatile building block in medicinal chemistry and materials synthesis, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo and ester functionalities. The trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the methyl ester facilitates subsequent derivatization. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for constructing complex aromatic scaffolds and heterocycles in high-throughput screening campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: