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Structure of 1214353-57-7
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Methyl 3-fluoro-2-nitrobenzoate features a fluorinated aromatic ring flanked by electron-withdrawing nitro and ester groups, enabling selective functionalization in synthetic sequences. This bench-stable derivative serves as a key intermediate for bioactive molecule construction, particularly in medicinal chemistry applications requiring controlled reactivity.
Methyl 3-fluoro-2-nitrobenzoate serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted benzimidazoles and other heterocyclic scaffolds via standard coupling and cyclization protocols. Its ortho-nitro and meta-fluoro functionalities provide complementary reactivity for sequential functionalization, while the methyl ester group supports reliable reduction or hydrolysis under mild conditions. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for high-throughput synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: