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Structure of 1214376-88-1
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5-Bromo-2-fluoro-3-iodopyridine features a trihalogenated pyridine core with distinct halogen positions enabling selective cross-coupling reactions. The electron-deficient ring facilitates palladium-catalyzed transformations, while the orthogonal reactivity of bromo, fluoro, and iodo substituents allows sequential functionalization. This compound serves as a key building block in the synthesis of bioactive heterocycles and advanced pharmaceutical intermediates.
5-Bromo-2-fluoro-3-iodopyridine serves as a versatile trihalogenated pyridine building block for palladium-catalyzed cross-coupling reactions. The strategically positioned bromo, fluoro, and iodo substituents enable sequential functionalization with high regiocontrol, facilitating the synthesis of complex heterocyclic scaffolds. Its bench-stable nature and compatibility with standard coupling conditions make it well-suited for iterative C–C and C–heteroatom bond formation in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: