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Structure of 1214900-52-3
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This boronate moiety features a chlorinated phenolic scaffold, enabling direct functionalization in Suzuki-Miyaura couplings. The hydroxyl group enhances solubility and provides a handle for derivatization, while the electron-deficient aryl ring facilitates palladium-catalyzed cross-coupling under standard conditions.
(3-Chloro-5-hydroxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling the efficient construction of biaryl scaffolds. The ortho-chloro and phenolic hydroxyl groups provide orthogonal reactivity for downstream functionalization, while the boronic acid moiety offers excellent bench stability and compatibility with aqueous workups. Its predictable coupling behavior and mild reaction conditions make it a reliable choice for synthesizing complex aromatic architectures in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: