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Structure of 1215916-40-7
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Methyl 5-bromo-2-methylnicotinate is a bench-stable, electron-deficient pyridine derivative featuring a bromine substituent at the C5 position and a methyl group at C2. This structural motif enables direct functionalization in cross-coupling reactions, facilitating rapid access to substituted heterocycles. The ester functionality enhances solubility in organic solvents and supports downstream derivatization.
Methyl 5-bromo-2-methylnicotinate serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-established bromine reactivity. The methyl ester group provides compatibility with standard hydrolysis and derivatization protocols, while the 2-methyl substituent enhances regiochemical control in electrophilic substitution. Its bench-stable nature and ease of purification make it suitable for iterative synthetic sequences in medicinal chemistry and process development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: