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Structure of 122143-19-5
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This cyclopropanecarboxylic acid derivative features a 2-chlorophenyl group attached to the cyclopropyl ring, delivering enhanced lipophilicity and metabolic stability. The carboxylic acid functionality enables direct coupling in synthetic routes, while the ortho-chloro substitution influences electronic properties and steric profile. Ideal for medicinal chemistry scaffolds requiring rigid, electron-deficient aryl motifs.
1-(2-Chlorophenyl)cyclopropanecarboxylic acid serves as a valuable building block in medicinal chemistry, enabling the synthesis of bioactive cyclopropyl-containing scaffolds. Its ortho-chlorinated aryl group enhances metabolic stability and modulates electronic properties, while the carboxylic acid functionality facilitates direct derivatization or coupling reactions. The molecule exhibits good bench stability and is compatible with standard synthetic transformations, including amide formation, esterification, and decarboxylation, making it a practical choice for targeted compound library development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: