(R)-2-Amino-5,5,5-trifluoropentanoic acid

Name: (R)-2-Amino-5,5,5-trifluoropentanoic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 122565-29-1
Cat. No. CS-0105959
Purity≥95%
MDL No.MFCD17676353

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(R)-2-Amino-5,5,5-trifluoropentanoic acid|CS-0105959

Structure of 122565-29-1

Size

Price

Quantity

* Please select Quantity before adding items.

Description

(R)-2-Amino-5,5,5-trifluoropentanoic acid features a chiral α-amino acid scaffold with a trifluoromethyl group at the γ-position, conferring enhanced metabolic stability and membrane permeability. This configuration delivers a potent bioisostere for natural amino acids in peptide-based drug design, enabling incorporation into peptidomimetics where resistance to enzymatic degradation is critical.

Application

(R)-2-Amino-5,5,5-trifluoropentanoic acid serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of fluorinated amino acid derivatives with enhanced metabolic stability. Its trifluoromethyl group imparts strong electron-withdrawing character and lipophilicity, while the stereogenic center supports enantioselective transformations. The compound exhibits bench stability and facilitates straightforward incorporation into peptide scaffolds and bioactive heterocycles via standard coupling and cyclization protocols.

General Information

CAS No. 122565-29-1
Cat. No. CS-0105959
Purity ≥95%
MDL No. MFCD17676353
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₈F₃NO₂
Molecular Weight 171.12
Synonym(s) None
SMILES C([C@H](C(O)=O)N)CC(F)(F)F

Computational Chemistry Data

TPSA 63.32
LogP 0.7408
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Alanine and derivatives

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

122565-29-1 sigma122565-29-1 manufacturer122565-29-1 price122565-29-1 structure122565-29-1 SDSbuy 122565-29-1122565-29-1 supplier122565-29-1 uses122565-29-1 molecular weightprice of 122565-29-1122565-29-1 chemical name formula of 122565-29-1

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(R)-2-Amino-5,5,5-trifluoropentanoic acid

CAS No. 122565-29-1

Recommended Products