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Structure of 1227489-83-9
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5-Bromo-3-(trifluoromethyl)picolinaldehyde features a trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the bromo substituent enables downstream cross-coupling. This aldehyde serves as a key building block in medicinal chemistry for constructing bioactive heterocycles under standard conditions.
5-Bromo-3-(trifluoromethyl)picolinaldehyde serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its bromo and aldehyde functionalities. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the aldehyde facilitates condensation reactions for heterocycle synthesis. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for constructing complex scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: